Early Beta-Blocker Administration Is Associated with Better Survival After STEMI

In the study below, the probability of death after 48 hours was 11% with immediate treatment versus 19% with delayed treatment.
However I would reserve the use of bisoprolol 2.5mg in the hypertensive patient with STEMI until practice is endorsed by more RCTs and/or AHA/ACC.

Hirschl MM et al. Benefit of immediate beta-blocker therapy on mortality in patients with ST-segment elevation myocardial infarction. Crit Care Med 2013 Mar 29;